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Interestingly, on undergoing a LOsG/ROS stress, β-cells started to re-express fetal nuclear Neurog3 and to dramatically relocate pancreas/duodenum homeobox protein 1 (Pdx1) from the cytoplasm to the nucleus (Fig

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Similarly, many large-molecule ferroptosis inhibitors struggle to penetrate cell membranes effectively, hindering their ability to exert intracellular effects